Clovedin® is an innovative plant-based raw material for the formulation of dietary supplements. It contains essential oil of Cinnamon and Clove with the addition of vitamin A. It provides valuable support for the balance of antioxidant defenses and the well-being of mucous membranes, making it highly useful for managing disorders that may arise in the case of intestinal and vaginal mycosis, including recurring ones.
The best ally for your intimate well-being. Contributes to the physiological balance of digestive functions and mucosal well-being.
CLOVEDIN® - COMPLETELY NATURAL
Clovedin® is a blend based on Clove Essential Oil (Syzygium aromaticum Merr. et L.M. Perry) with a high content of eugenol, Cinnamon Essential Oil (Cinnamomum cassia J. Presl.) with a high content of cinnamaldehyde, and Vitamin A.
The two essential oils work synergistically to promote digestive balance and antioxidant defenses, while Vitamin A supports mucosal well-being.
Clovedin® can be used as a raw material for dietary supplements for intimate well-being.
In vitro experiments have been conducted on Clovedin® ingredients at the University of Bologna, confirming the synergistic action of its ingredients in combating the proliferation of 18 strains of Candida spp., while respecting the species known for their protective actions on intimate well-being, such as Lactobacillus acidophilus. Currently, a double-blind, placebo-controlled clinical study is underway in collaboration with various specialists from Emilia-Romagna and Liguria centers, focusing on patients with recurrent candidiasis.
In Europe Registered
TGD s.r.l. has registered Clovedin® in Europe for the production of supplements to support antioxidant defenses and mucosal well-being.
What is Clovedin® used for?
Why are Cinnamon and Clove essential oils included?
The essential oils of Cinnamon (Cinnamomum cassia J. Presl.) and Clove (Syzygium aromaticum Merr. et L.M. Perry) have shown synergistic action in our in vitro experiments in combating the proliferation of 18 strains belonging to the Candida genus, including those resistant to major antifungal agents, without altering the vitality of lactobacilli, which are of fundamental importance for the well-being of the vaginal microbiota. The unique formulation of the product allows the two essential oils to bypass the stomach and act in the colon, where alterations of the intestinal microbiota, including the excessive proliferation of Candida spp., commonly occur.
What is the purpose of Vitamin A?
Vitamin A is an essential fat-soluble micronutrient, and its food sources include both preformed vitamin A (mainly retinol and retinyl esters) in animal-derived foods and its precursors in plant-derived foods, such as carotenoids. Its importance lies in its involvement in physiological processes related to vision, as well as in stimulating tissue repair, including epithelial and mucosal tissues, including genital mucosa.
Why is Clovedin® an innovative product?
The essential oils in Clovedin® are in a gastro-resistant formulation, which allows them to not be absorbed by the body and to be released directly into the colon. Here, they help promote digestive functions. The balance of digestive functions is directly related to the balance of the intestinal microbiota. The excessive proliferation of opportunistic pathogenic microorganisms, including Candida spp., can lead to imbalances and the development of various pathologies.
Is Clovedin® a safe ingredient?
Based on scientific evidence, the essential oil of Cinnamon (Cinnamomum cassia J. Presl.) and Clove (Syzygium aromaticum) are considered safe. Both are recognized as GRAS (Generally Recognized As Safe) by the FDA and EFSA.
How is Clovedin® produced?
The essential oils of Cinnamon (Cinnamomum cassia J. Presl) and Clove (Syzygium aromaticum Merr. et L.M. Perry) undergo a microencapsulation process, followed by blending with Vitamin A.
Is Clovedin® free from Genetically Modified Organisms (GMOs)?
Clovedin® is GMO-free. It does not contain, derive from, or consist of Genetically Modified Organisms. Clovedin® complies with Regulations EC 1829/2003 and 1830/2003. Specifically, Regulation (EC) No. 1829/2003 of the European Parliament and of the Council of 22 September 2003 on genetically modified food and feed, and Regulation (EC) No. 1830/2003 of the European Parliament and of the Council of 22 September 2003 concerning the traceability and labeling of genetically modified organisms and the traceability of food and feed products produced from genetically modified organisms.
Where do the ingredients of Clovedin® come from?
The essential oil of cloves comes from Indonesia, and the essential oil of cinnamon comes from China. All the raw materials are processed in Italy.
Has Clovedin® been clinically tested?
After the promising results of the in vitro study, the research is continuing, and currently, a double-blind, placebo-controlled clinical trial is being initiated in patients with recurrent candidiasis in collaboration with various specialists operating in Emilia-Romagna and Liguria centers.
Is the product formulation patented?
The formulation of Clovedin® is covered by European patent no. WO2023275020.
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