{"id":1877,"date":"2023-08-07T08:00:00","date_gmt":"2023-08-07T06:00:00","guid":{"rendered":"https:\/\/www.tgd.care\/bowel-inflammation-eubiotic\/"},"modified":"2025-01-14T15:28:08","modified_gmt":"2025-01-14T14:28:08","slug":"bowel-inflammation-eubiotic","status":"publish","type":"post","link":"https:\/\/www.tgd.care\/en\/articles\/bowel-inflammation-eubiotic\/","title":{"rendered":"Bowel inflammation and eubiotic solutions"},"content":{"rendered":"\n<p>Bowel inflammation is a condition associated with diseases of varying severity (such as Inflammatory Bowel Diseases, Irritable Bowel Syndrome, metabolic disorders) and the natural aging process of the body. In a gut with a balanced <a href=\"\/en\/not-categorized\/gut-microbiota-what-it-it\/\" target=\"_blank\" rel=\"noreferrer noopener\">microbiota<\/a> (eubiosis), there are microbial families that exert a significant protective effect on overall health. Specifically, these microorganisms produce <strong>short-chain fatty acids<\/strong> (propionate, acetate, and butyrate, abbreviated as SCFA), which can<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li> <strong>promote intestinal barrier integrity<\/strong>,<\/li>\n\n\n\n<li><strong>enhance emotional and cognitive well-being<\/strong> through communication with the nervous system,<\/li>\n\n\n\n<li><strong>regulate energy metabolism<\/strong>, and<\/li>\n\n\n\n<li><strong>boost immune system<\/strong> efficiency. <\/li>\n<\/ul>\n\n\n\n<p>Notably, 70% of immune cells are found in the gut.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Bowel inflammation causes<\/h2>\n\n\n\n<p>External factors, like unbalanced diet, sedentary lifestyle, indiscriminate use of antibiotics, and stress, <strong>can disrupt this balance<\/strong>. Specifically, there is always<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>a decrease in families that produce protective compounds (SCFA) and<\/li>\n\n\n\n<li>an <strong>increase in so-called opportunistic pathogens<\/strong>.<\/li>\n<\/ul>\n\n\n\n<p>These are microbial families naturally present in the microbiota but can cause disease if their proliferation is excessive. These microorganisms preferentially use proteins as their energy source and thus have a proteolytic metabolism. This leads to the <strong>biosynthesis of phenolic, indolic, and methylamine compounds<\/strong>, such as indole, skatole, and trimethylamine. These substances have a direct correlation with <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>intestinal inflammation,<\/strong><\/li>\n\n\n\n<li><strong>thinning of the protective mucus layer<\/strong> of the mucosa resulting in <\/li>\n\n\n\n<li><strong>immune system activation<\/strong>, and <\/li>\n\n\n\n<li><strong>increased intestinal permeability<\/strong> (leaky gut).<\/li>\n<\/ul>\n\n\n\n<p>This sets up a <strong>vicious cycle<\/strong> in which the proliferation of opportunistic pathogens supports excessive immune system activation. Consequently, inflammation creates ideal conditions for the growth of opportunistic pathogens and further supports intestinal dysbiosis.<\/p>\n\n\n\n<p>These conditions are also present in scenarios not strictly pathological, such as aging. In fact, the composition of the microbiota tends to change with <strong>advancing age<\/strong>, with an increase in opportunistic pathogens and a reduction in microorganisms with protective effects. Even without significant pathologies, the phenomenon known as <em><strong>&#8220;inflammaging&#8221;<\/strong><\/em> is observed, a term that describes a chronic low-grade inflammation directly correlated with aging processes.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Innovative solutions<\/h2>\n\n\n\n<p>Currently, in cases of dysbiosis, nutritional and pharmacological interventions do not always yield the desired results. Therefore, valuable support can come from plant derivatives that have shown to promote intestinal well-being. Our research group at the University of Bologna has analyzed a series of compounds found in the essential oils of various plants. Among these, the <strong>essential oil of Palmarosa<\/strong> (<em>Cymbopogon martinii<\/em>), that contains geraniol, has demonstrated excellent effects in reducing intestinal inflammation, promoting intestinal barrier integrity, and restoring microbiota eubiosis in preclinical analyses and human trials.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><a href=\"https:\/\/amzn.eu\/d\/2ZgdfUw\" target=\"_blank\" rel=\"noreferrer noopener\"><img decoding=\"async\" src=\"https:\/\/www.tgd.care\/wp-content\/uploads\/2025\/01\/bowel-inflammation-biointestil-1024x854.jpg\" alt=\"bowel inflammation biointestil\" class=\"wp-image-3473\"\/><\/a><\/figure>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-16018d1d wp-block-buttons-is-layout-flex\">\n<div class=\"wp-block-button\"><a class=\"wp-block-button__link wp-element-button\" href=\"https:\/\/amzn.eu\/d\/2ZgdfUw\" target=\"_blank\" rel=\"noreferrer noopener\">BUY ON AMAZON<\/a><\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Bowel inflammation is a condition associated with diseases of varying severity (such as Inflammatory Bowel Diseases, Irritable Bowel Syndrome, metabolic disorders) and the natural aging process of the body. In a gut with a balanced microbiota (eubiosis), there are microbial families that exert a significant protective effect on overall health. Specifically, these microorganisms produce short-chain&#8230;<\/p>\n","protected":false},"author":1,"featured_media":1369,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[37,39],"tags":[],"class_list":["post-1877","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-articles","category-digestion"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.7 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Bowel inflammation and eubiotic solutions<\/title>\n<meta name=\"description\" content=\"Discover What Bowel Inflammation Is, What Causes It, and the Innovative Remedies Offered by the World of Research.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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